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It is with great sadness that we write to inform you that will be closed with effect from the 30th of September 2023.
It has been our privilege to look after you, our PGP “extended family”, which includes over 30,000 patients during our 28-year history.
Our integrative work has been groundbreaking with some truly remarkable and humbling results for which, I believe, we became quite famous.
I would like to thank past and present patients and staff for your tremendous work as an extended team, together with our network of colleagues throughout the UK.
We have worked very hard to try and ensure a smooth transition for your healthcare.
We hope that the information below will be helpful to you.

Your future medical care

It is important that you have access to your NHS GP or other medical service in future should you need prescription-based medications. We are unable to recommend a medical practice but may be able to signpost you to appropriate support via
If you have special requirements as a past patient please email Responses are not guaranteed and will be discretionary.

How we handle your data

We have a legal duty to inform you of the way we are managing your data. Over the past two or three years, our policy has been to send you copies of all your letters, blood results, and notes from your consultations. Therefore, you should have enough information to provide any new GMC-registered medical practitioner.
Past medical records are held securely. Please send any SARS requests to

PGP still retains the contact data of all patients with an email address. This is with a view to making future contact to advise of any services being provided by PGP going forward. All patients are offered the option of opting out of this and having their contact data removed if they so wish.

Yours in health and happiness.
The PGP Team


This condition is becoming more quoted and well known in the UK. At its worst it represents a clinical picture of persistent histamine release, encouraging symptoms of true allergy including those symptoms that occur in anaphylaxis.

These symptoms might include lip swelling, airway constriction, urticarial type rashes on the skin, a wheezy chest, low blood pressure, fainting attacks and others including hypersensitivity “to almost  everything”.

In all probability, this condition, does not occur in isolation and it often coexists with a dysregulated immune system, problems with the gut, inflammation caused by multiple factors, and dysregulation of the ecosystem.

Histamine has an affect on over 80 different chemicals in the body so when it is showing high levels in the body, it causes multiple symptoms and has multiple effects.

We are all aware of hayfever caused by an allergy to grass or tree pollen in the spring and summer months of the year. This too is caused by excessive histamine and the treatment used in the traditional medical world tends to be a prescription for antihistamines.

MCAS itself can be difficult to diagnose as test results  can often be normal unless there are significant symptoms present at the time of doing the test.

In the UK, there are various tests relating to histamine levels, the measurement of diamine oxidase, & other specialist tests that we can organise for you.

If necessary we can refer you for allergy skin prick tests that can be used to help diagnose your condition and the causes of your symptoms. Various treatments that also include desensitisation may be possible.

A discussion with One of our Functional Doctors  will include the roots of MCAS eg gut dysfunction; fatty acid imbalances; and others.  The use of licensed medications can sometimes help and where appropriate, the occasional use of off license medications depending upon whether licensed medications have been well tried and documented. Your doctor will guide you through what might be possible.

You are unique and we are ready to listen

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